摘要
目的：总结持续气道内正压通气（ＣＰＡＰ）对阻塞型睡眠呼吸暂停综合征（ＯＳＡＳ）患者的治疗经验。方法：经多导睡眠呼吸监测图（ＰＳＧ）对１１０例就诊病人进行监测，诊断ＯＳＡＳ９６例，对其中接受ＣＰＡＰ治疗的１５例病人记录治疗前后睡眠呼吸监测图有关数据并应用配对ｔ检验，对所测结果进行统计学处理。结果：治疗后所有病人症状改善，血氧饱和度（ＳａＯ２）明显升高（Ｐ＜０．００１），舒张压有所降低（Ｐ＜０．０５），总共低通气时间明显缩短（Ｐ＜０．０１），呼吸紊乱指数（ＡＨＩ）明显降低（Ｐ＜０．００１）。醒觉时间明显缩短（Ｐ＜０．００１），醒觉时间占记录时间百分比值有明显减少（Ｐ＜０．０５）。结论：ＣＰＡＰ对ＯＳＡＳ患者治疗有效，但需在内科医生直接指导下进行。对致死性窒息性呼吸衰竭。
Objective: It was aimed to evaluate the therapeutic effect of ventilation with continuous positive airway pressure (CPAP) on patients with obstructive sleep apnea syndrome (OSAS). Methods: Fifteen cases of OSAS diagnosed clinically and by figures made by PSG and all data before and after treatment with CPAP were analysed for comparison. Results: All patients showed symptomatic improvement after treatment. SaO 2 increased, diastolic blood pressure improved, total hypoventilation time shortened, AHI reduced, awake time and the ratio of awake time to the recorded time decreased (P<0.05￣0.001). There were no significant changes about the longest and averange apnea time, the systolic blood pressure, the awake time and the number of awakening (P>0.05) respectivealy. This may probably be due to lesser cases to be involved. Three out of fifteen cases failed to get favorable effect after intial CPAP treatment and its causative factors were discussed briefly. Conclusions: CPAP ventilation is effective in the treatment of OSAS with significant symptomatic improvement and benefits to hypoxia and dysventilation. CPAP ventilation should be properly directed by the medical physician. In case of fatal suffocation happened, tracheostomy is indicated and is life saving.
关键词
睡眠呼吸暂停
综合征
CPAP
睡眠性
机械通气
obstructive sleep apnea syndrome(OSAS)
cntinuous positive airway pressure(CPAP)
BiPAP
AHI
SaO 2
