期刊文献+

他克莫司软膏治疗口腔糜烂型扁平苔藓的疗效观察 被引量:18

Observation of therapeutic effect of Tacrolimus ointment on patients with erosive oral lichen planus
暂未订购
导出
摘要 为观察局部应用他克莫司软膏治疗口腔糜烂型扁平苔藓的疗效,选择口腔糜烂型扁平苔藓患者62例并随机分成2组,分别用他克莫司软膏和丙酸氯倍他索软膏治疗。随访观察治疗6月后显效率、不良反应和停药6月后复发率,2组差异无显著性。0.03%他克莫司软膏治疗口腔糜烂型扁平苔藓具有良好的临床疗效。 To investigate the effects of Tacrolimus ointment on patients with erosive oral lichen planus.A total of 62 cases were collected and divided into two groups randomly: 31 cases were treated with Tacrolimus ointment(treatment group),and 31 cases with clobetasol propionate ointment(control group).There was no significant difference between two groups of the effective rate and side-effect occurrence during the therapy,and relapse rate within six months after treatment.The results of the present work demonstrate that Tacrolimus ointment is an effective therapy for oral lichen planus.
出处 《实用口腔医学杂志》 CAS CSCD 北大核心 2010年第1期108-109,共2页 Journal of Practical Stomatology
关键词 他克莫司 丙酸氯倍他索 扁平苔藓 糜烂型 Tacrolimus Clobetasol propionate Lichen planus Erosion
  • 相关文献

参考文献5

  • 1Conrotto D, Carbone M, Carrozzo M, et al. Ciclosporin vs. clobetasol in the topical management of atrophic and erosive oral lichen planus: A double-blind, randomized controlled trial[J]. Br J Dermaol, 2006, 154( 1 ) : 139 - 145.
  • 2周刚,刘宏伟,林梅,唐国瑶.口腔扁平苔藓(萎缩型、糜烂型)疗效评价标准(试行)[J].中华口腔医学杂志,2005,40(2):92-93. 被引量:387
  • 3何亚丽,郭在培.外用他克莫司在皮肤科的应用[J].中国麻风皮肤病杂志,2008,24(6):469-471. 被引量:25
  • 4Olivier V, Lacour JP, Mousnier A, et al. Treatment of chronic erosive oral lichen planus with low concentrations of topical tacrolimus: An open prospective study [ J ]. Arch Dermatol, 2002, 138(10) :1335 - 1338.
  • 5Lozada-Nur FI, Sroussi HY. Tacrolimus powder in orabase 0.1% for the treatment of oral lichen planus and oral lichenoid lesions: An open clinical trial [ J ]. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 2006, 102(6) :744 -749.

二级参考文献18

  • 1郝飞,钟华.他克莫司软膏治疗面部糖皮质激素依赖性皮炎临床疗效观察[J].临床皮肤科杂志,2007,36(1):54-56. 被引量:123
  • 2潘炜华,刘晓刚,温海.他克莫司软膏治疗激素依赖性皮炎的疗效观察[J].中国美容医学,2007,16(1):78-79. 被引量:8
  • 3靳培英.皮肤病药物治疗.北京:人民卫生出版社,2003.522-524.
  • 4Panhans- Gross A, Novak N, Kraft S, et al. Human epidermal Langerhans' cells are target for the immunosuppressive macrolide tacrohmus (FK - 506). J Allergy Clin Immtmol 2001 ; 107:345.
  • 5Lauermua AL, Surber C, Maibach HI. Absorption of topical tacrolimus ointment for atopic dermatitis (FK506) in vitro through human skin: comparisnon with cyclosporin A. Skill Pharmacol 1997; 10: 230 - 234.
  • 6Ruzicka T, Assmamn T, Homey B. Tacrolimus: the drug for the turn of the millernnium. Arch Dermatol 1999; 135:574 - 580.
  • 7Schachner LA, Lamerson C, SheehanM P, et al. Tacrolimus ointment 0.03 % is safe and effective for the treatment of mild to moderate atopic dermatitis in pediatric patients: results from a randomized, double - blind, vehicle - controlled study. Pediatrics 2005 ; 116 : 334 - 342.
  • 8Hanifin JM, Ling MR, Langley R, et al. Tacrolimus ointment for the treatment of atopic dermatitis in adult patients. J Am Acad Dermatol 2001 ;44:28 - 38.
  • 9Rallis E, Nasiopoulou A, KouskoukisC, et al. Successful treatment of genital and facial psoriasis with tacrolimus ointment 0.1%. J Drugs Dermatol 2005 ; 5 : 906 - 907.
  • 10Carroll CL, Clarke Ja, Camacho F, et al. Topical tacrolimus ointment combined with 6% salicylic acid gel for plaque psoriasis treatment. Arch Dermatol 2005 ; 141-43 - 46.

共引文献405

同被引文献141

引证文献18

二级引证文献114

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部