摘要
目的:促进临床合理用药。方法:参考有关文献、期刊,结合临床用药实践,介绍不同药物的时辰药效学、药动学和时辰毒性的差异。结果:同一药物在一天中不同时间给药,其疗效和毒性不同。结论:根据时辰药理学,在最佳时间内服药,可以提高疗效,减少不良反应。
OBJECTIVE： To promote rational use of drugs in clinic. METHODS： The difference of chronopharmacodynamics, chronopharmacokinetics and chronotoxicity of drugs were introduced, referring to the relevant literatures, journals and practices. RESULTS： The same drug represented different efficacy and toxicity for one day due to delivery at different time. CONCLUSION： According to chronopharmacology, administration at optimal time contributes to efficacy and reduces adverse reaction.
出处
《中国药房》
CAS
CSCD
北大核心
2010年第6期558-559,共2页
China Pharmacy
关键词
合理用药
不良反应
最佳给药时间
Rational drug use
Adverse reaction
Optimal time for administration
