摘要
目的观察倍他乐克联合辅酶Q10治疗扩张型心肌病的临床疗效及安全性。方法对66例扩张型心肌病患者随机分为两组,在限制体力活动低盐饮食、应用洋地黄利尿剂及ACEI制剂的基础上,实验组加用倍他乐克和辅酶Q10治疗。组间分别进行疗效观察。结果治疗3个月后实验组QT离散度、LVEF、SBP、DBP、HR及心功能分级与对照组比较均有显著性差异,未见特殊严重不良反应。结论倍他乐克联合辅酶Q10治疗扩张型心肌病可显著改善患者心功能和预后,降低猝死率,临床疗效可靠、安全。
Objective To observe the clinical efficacy and safety of betaloc combined with coenzyme Q10 for dilated cardiomyopathy. Methods We divided 66 cases of dilated cardiomyopathy randomly into two groups. Both groups were given limit physical activity,a low-salt diet,a small dose of digitalis diuretics and ACEI preparation,and betaloc and coenzyme Q10 were added to the treatment group. Comparison was made of curative effect between the two groups separately. Results 3 months after treatment,the QT dispersion,LVEF,SBP,DBP,HR and cardiac functional class in the treatment group were significantly different compared with the control group, with no specific serious adverse reactions. Conclusion Combination of betaloc and coenzyme Q10 in the treatment of dilated cardiomyopathy can significantly improve cardiac function and prognosis and reduce the sudden death rate, with reliable clinical efficacy and safety.
出处
《中国现代医生》
2010年第3期115-116,共2页
China Modern Doctor
