摘要
目的探讨油田医院临床分离的革兰阳性球菌的耐药特征，为临床医师合理用药提供依据。方法317株革兰阳性球菌分离自医院2006年1月~2008年12月临床送检的各类感染性标本，革兰阳性球菌培养与鉴定严格按照《全国临床检验操作规程》进行，药物敏感试验采用K—B法。结果317株革兰阳性球菌中金黄色葡萄球菌、凝固酶阴性葡萄球菌、粪肠球菌分离率分别居第1、2、3位；耐甲氧西林金黄色葡萄球菌（MRSA）检出率为39．1％，耐甲氧西林凝固酶阴性葡萄球菌（MRCNS）检出率为36．0％；革兰阳性球菌对常用抗菌药物产生了不同程度的耐药性，仅对糖肽类抗菌药物100．0％敏感。结论务必加强医院感染管理工作，严防耐药菌株传播与流行。
OBJECTIVE To approach drug-resistance status of clinically isolated Gram-positive cocci in an oil field hospital and provide the evidence for clinically reasonable use of antibiotics. METHODS A total of 317 strains of Gram-positive cocci were isolated from all kinds of contaminated specimens from Jan 2006 to Dec 2008 in an oil field hospital. Organisms were cultivated and identified according to National Clinical Laboratory Operation Rule. The drug sensitivity testing was performed by K-B methods. RESULTS Among the 317 strains, the isolating rate of Staphylococcus aureus, coagulase-negative Staphylococcus, Enterococcus faecalis ranked the first three, respectively. The detection rate of meticillin-resistant Staphylococcus aureus （MRSA） was 39. 1%, and that of meticillin-resistant coagulase-negative Staphylococcus （MRCNS） was 36. 0%. The Gram-positive cocci were resistant to the commonly used antibiotics in different degrees except for 100% sensitivity to g!ycopeptide antibiotics. CONCLUSIONS We should strengthen the management of nosoeomial infections to prevent the dissemination and epidemic of drug-resistant strains.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2010年第3期417-418,共2页
Chinese Journal of Nosocomiology
关键词
革兰阳性球菌
耐甲氧西林葡萄球菌
耐药性
Gram-positive coccus
Meticillin-resistant Staphylococcus
Drug-resistance
