摘要
目的了解2006年1月至2008年12月本院铜绿假单胞菌的分布及对不同类型抗菌药物的耐药情况,以指导临床合理用药。方法收集临床送检分离的铜绿假单胞菌进行耐药性监测,采用纸片扩散法(K-B法)进行监测,结果根据美国临床实验室标准化委员会(NCCLS)相关文件判断。结果铜绿假单胞菌对氨苄西林、复方新诺明、头孢噻肟的耐药率均大于40%,对亚胺培南的耐药率最低,约为5%。结论铜绿假单胞菌仍是医院病原菌感染的主要致病菌之一,加强耐药性监测,合理应用抗菌药物是十分重要的。
Objective To investigate the change in antimicrobial resistance to Pseudomonas aeruginosa in our haspital from Jan,2006 to Dee,2008 and to direct the using of drugs reasonably. Methods The clinically isolated P. aeruginosa strains were collected, surveillance of drug resistance by paper diffusing method, the results were evaluated according to the relevant documents of NCCLS of USA. Results The resistant rates of P. aeruginosa to AMP,SMI, and CTX were higher than 40 %. The resistant rate to IMP was the lowest （about 50% or so ）. Conclusion P. aeruginosa is still a major pathogenic bacterium in our hospital. It is very important to select antibiatics correctly according to the results of susceptibility tests.
出处
《检验医学与临床》
CAS
2010年第3期220-220,223,共2页
Laboratory Medicine and Clinic
关键词
铜绿假单胞菌
标本分布
药物耐药性监测
pseudomonas aeraginosa
distribution of samples
surveillance of drug resistance
