摘要
目的探讨原发性高血压患者颈动脉内膜中层厚度（IMT）的变化及其与脑卒中的关系。方法应用高频彩色多普勒超声检测100例原发性高血压患者与60例健康体检者IMT值，分析其变化，并通过随访，了解高血压患者IMT与脑卒中的关系。结果（1）原发性高血压患者IMT值明显高于健康者（P〈0．01）。（2）不稳定性斑块发生脑卒中的比率明显增加（P〈0．01）。结论通过了解高血压患者IMT与颈动脉斑块性质可预测其发生脑卒中的概率，为临床防治提供依据。
Objective To explore the variation of carotid intima - media thickness （IMT） in essential hypertension （EH） patients and the relationship between IMT and stoke. Methods To detect the values and analyze the variation of IMT in 100 EH patients and 60 healthy people with high - frequency color Doppler ultrasound test instrument. And analyze the relationship between IMT and stoke after 5 years follow - up. Results （1） The values of IMT in EH patients are obviously higher than control group （P〈 0.01）, （2） The occurrence rate of stoke is obviously increased in the EH patients with the plaque instability in carotid artery （ P 〈 0.01 ） Conclusion By analyzing the values of IMT and the quality of the carotid artery plaque can predict the probability of occurrence of stoke, and provide a basis for clinical prevention and treatment.
关键词
原发性高血压
颈动脉内膜中层厚度
脑卒中
essential hypertension （EH）
carotid intima - media thickness （IMT）
stroke
