摘要
目的探讨磁敏感成像（SWI）在急性缺血性脑卒中（AIS）出血转化（HT）中的应用价值。方法对18例症状出现6 h内的AIS患者行常规MRI及SWI检查,静脉溶栓后12周复查CT或MRI。根据复查时有无出血将其分为出血组（HT组）和无出血组（无HT组）,分析溶栓前两组的SWI影像特征。结果8例超急性期缺血性脑卒中患者无HT组15例,HT组3例。HT在SWI上呈显著低信号。溶栓前HT组中2例SWI上可见大脑中动脉行径粗大低信号影,2例见缺血区内微出血灶,1例见缺血区异常静脉影;无HT组均未见大脑中动脉粗大低信号影和缺血区异常静脉影,2例有缺血区外微出血灶。结论急性缺血性脑卒中SWI上大脑中动脉行径粗大低信号影、缺血区异常静脉血管影和微出血灶等征象可能与HT有关。SWI可为AIS治疗方案的选择提供重要信息。
Objective To investigate the application value of susceptibility-weighted imaging（SWI） in hemorrhagic transformation（HT） in patients with acute ischemic stroke（AIS）.Methods Conventional MRI and SWI were performed in 18 patients with AIS within 6 days of symptom onset.Follow-up CT or MRI was performed within 1-2 weeks after thrombolytic therapy to evaluate hemorrhage.The patients were divided into HT group and Non-HT group and their features of SWI were analyzed.Results Of the 18 patients with hyperacute ischemic stroke,15 were in Non-HT group and 3 in HT group.Significant hypointensity was revealed on SWI in patients with HT.In HT group,2 patients presented hypointensity along the course of the middle cerebral artery（MCA）,2 patients had microbleeds in ischemic lesions and 1 patient showed abnormal veins on SWI.In Non-HT group,no hypointensity along the course of MCA or abnormal veins were detected on SWI,except 2 patients with microbleeds outside loci of lesions.Conclusion Hypointensity along the course of MCA,abnormal veins and microbleeds on SWI might be associated with HT in hyperacute ischemic stroke.SWI can provide important information for clinical AIS regimen.
出处
《徐州医学院学报》
CAS
2010年第1期57-59,共3页
Acta Academiae Medicinae Xuzhou
关键词
急性缺血性脑卒中
出血性转化
磁共振成像
磁敏感成像
acute ischemic stroke
hemorrhagic transformation
magnetic resonance imaging
susceptibility -weighted imaging
