摘要
为比较Ａｌｚｈｅｉｍｅｒ病（ＡＤ）和老年精神分裂症（ＳＳ）患者脑电图（ＥＥＧ）的各自特点。方法对３２例ＡＤ患者、２４例ＳＳ患者及３９例正常老人，使用丹麦ＳＥＥＧ—１６道脑电图仪，完成ＥＥＧ检查。结果ＡＤ患者ＥＥＧ异常率８７．５％，显著高于ＳＳ患者的６６．７％和正常老人的２８．２％。（Ｘ检验，Ｐ＜０．０１）。ＡＤ患者、ＳＳ患者分别较正常老人慢波活动及α慢波化显著增加（Ｘ检验，Ｐ＜０．０１）。ＡＤ患者和正常老人２个年龄组的异常率随年龄增大而增高。ＡＤ患者和正常老人ＥＥＧ检查结果与ＣＡＳＩ量表分之间存有一定关系，但在ＳＳ患者中则否。结论ＡＤ患者和ＳＳ患者的ＥＥＧ表现出具有不同于正常衰老的变异，且ＡＤ和ＳＳ在＜８．５Ｈｚα波上有明显差异，因而ＥＥＧ对了解ＡＤ患者和ＳＳ患者及两个疾病鉴别上仍有一定参考价值。
Objective To investigate the variations of electroencephalogram(EEG) of aged patients with Alzheimer's disease(AD)and chronic schizophrenia.Methods The BEAM-EEG was recorded from the scalps of 32 patients diagnosed as AD according to DSM-Ⅲ-R,24 patients diagnosed as chronic schizophrenia according to CCMD-Ⅱ-R and 39 normally aged controls,using a Dantec Concerto SEEG-16 Instrument.Results Compared with that of normal controls(28.2%) and of schizophrenics(66.7%),the abnormal ratio of EEG was significantly higher in AD patients(87.5%,P<0.05).The varied EEG was presented as slower α wave(<8.5Hz),increased θ and δ waves.Both AD patients and normal controls showed their EEG further abnormal as their age increased.The relationship between EEG and one cognitive assessment-CASI score was also found within the AD group,but in was not found within schizophrenia group.Conclusions The variations of EEG between AD patients and aged schizophrenics were confirmed in the present study,and their clinical significances were suggested.
出处
《四川精神卫生》
1998年第2期73-76,共4页
Sichuan Mental Health
关键词
ALZHEIMER病
老年精神分裂症
脑电图
脑电描记术
Alzheimer's disease(AD) Electroencephalogram(EEG) Chronic schizophrenia Aged patients Normal aged
