摘要
应用公认的确定盐敏感性的方法检出一定数量的盐敏感者和不敏感者，用病例（盐敏感者）对照（盐不敏感者）研究方法对比分析他们的特征，确定与盐敏感相关最显著的指标，为今后筛选盐敏感者方法提供基础。单因素分析结果表明：在原发性高血压病人组，盐敏感性与基线、钠饱和期及钠消耗期红细胞钠／锂反运转率，钠消耗期尿钠排泄量、钠消耗期血浆醛固酮水平等有关，对可能混杂变量进行调整，用非条件Ｌｏ－ｇｉｓｔｉｃ回归模型分析，结果表明只有基线钠／锂反运转率被引入主效应方程，提示了它是盐敏感性的重要筛选指标。
The present study used a standardized protocol of intravascular volume expansion and contraction to identify salt sensitive(SS) and resistant individuals, then compared and analyzed the characteristic of salt sensitivity by use of the case control study to find out salt sensitivity related indicators for providing the basic data on screening method of salt sensitivity. The results of single factor analysis showed that SS was closely related to the three factors:①Na +/Li +CT(countertransport) during baseline, sodium loading, and sodium and volume depletion,②plasma aldosterone concentrations during sodium and volume depletion,③sodium excretion during sodium and volume depletion. Based on single factor analysis, the joint effect of related factors was examined with unconditional Logistic regression model. The result showed that only Na +/Li +CT of baseline was got into the equation.
出处
《中国慢性病预防与控制》
CAS
1998年第5期231-234,共4页
Chinese Journal of Prevention and Control of Chronic Diseases
