摘要
目的研究慢性泄泻虚实证患者植物神经功能状态，并探讨中药复方泄泻灵的治疗作用．方法慢性泄泻患者３１例，女１９例，男１２例，虚证１８例，实证１３例，正常对照组３１例．泄泻组采用复方泄泻灵治疗４ｗｋ，并对其治疗前后植物神经（ＡＮＳ）功能状态进行检测．结果慢性泄泻患者存在ＡＮＳ功能异常状态．其中，虚证患者以副交感神经功能增强为主，实证患者以交感神经功能增强为主，二者存在明显差异性（Ｐ＜００１），中药复方泄泻灵有调整慢性泄泻虚实证患者ＡＮＳ功能状态的作用（Ｐ＜００１）．结论慢性泄泻患者ＡＮＳ功能状态的测定，可作为该病虚实辨证的参考指标之一，中药复方泄泻灵可作为调整慢性泄泻患者ＡＮＳ功能状态的有效方剂．
AIM To study the autonomic nervous system (ANS) functions in patients with chronic diarrhoea of deficiency/excessiveness syndrome and the effect of Xiexieling recipe. METHODS Thirty one chronic diarrhea patients (19 women and 12 men, 18 cases of deficiency syndrome and 13 of excessiveness syndrome) and 31 normal subjects were investigated. The ANS functions in patients with chronic diarrhea of deficiency/excessiveness syndrome were tested before and 4 weeks after treatment by Chinese herbs complex Xiexieling recipe. RESULTS The ANS functions in diarrhea patients were significantly different in comparing with the healthy group. The patients with deficiency syndrome were mostly with predominant parasympathetic tonus, while the patients with excessiveness syndrome with predominal sympathetic, the significant difference between two syndromes was found ( P <0 01) . The ANS functions in the deficiency and excessiveness syndromes were regulated obviously towards normal after treatment ( P <0 01). CONCLUSION The ANS function is regarded as a good referential parameter in classification of deficiency/excessiveness syndrome differentiation in chronic diarrhoea, and Xiexieling is the effective recipe modulating the ANS functions.
基金
广东省中医药管理局基金
关键词
中医药疗法
腹泻
诊断
自主神经系统
泄泻灵
diarrhea/diagnosis
diarrhea/therapy
drugs, Chinese herbal
autonomic nervous system
