摘要
本项研究通过对29例患者31块行术后放疗的口腔颌面部各类组织瓣的临床观察，并就急性放射反应与周围组织进行比较，结果表明，口腔内组织瓣的急性放射反应发生率明显低于周围粘膜（P＜0．08）；而口外组织瓣与皮肤之间，以及带蒂与游离组织瓣之间的放疗耐受性无明显差异（P＞0．05）。31块组织瓣在放疗期间以及放疗后无一发生不可逆性放射性损伤，表明各类组织瓣对目前临床常规采用的术后放疗具有良好的耐受性。
Twenty-nine patients owing thirty-one flaps were followed during the postoperative radiation therapy. It wasfound that the acute toxicity ratio of the flaps in the oral cavity was significantly less than that of mucosa in thesame irradiation field(P＜0. 05); whereas it was no significant when comparing the flaps out of the oral cavity tothe same radiated skin (P＜0. 05),Such was the comparison of the free flaps and pedicled ones (P＜0. 05). All thechangs resulting from radiation therapy in the flaps were found to be acceptable. Therefore the author concludesthat, all kinds of flap are well tolerant to the postoperative radiotherapy while the starting time to the operation ismore than three weeks and the dosage less than 70Gy rad. Furthermore, the approximate time for postoperativeradiotherapy may be earlier if the flaps are thought to be well healed, as well as the top dosage may be increased ifthe treatmeat demands.
出处
《口腔颌面外科杂志》
CAS
1998年第3期167-169,共3页
Journal of Oral and Maxillofacial Surgery
