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幽门螺旋杆菌感染与冠心病的相关性探讨 被引量：7

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摘要 目的探讨幽门螺杆菌(HP)感染及其不同毒力与冠心病(CHD)的关系及其对血清免疫学的影响,并探讨其可能的发病机制。方法应用ELISA法测定286例冠心病患者和100例冠脉造影正常者(对照组)血清HP特异性抗体(HP IgG、HP IgM),及其细胞毒素相关蛋白特异性抗体浓度,结果冠心病组血清幽门螺杆菌IgG,IgM阳性率均明显高于对照组(P<0.01),急性冠脉综合征(ACS)组血清幽门螺杆菌HP IgG阳性率及HP IgM阳性率高于其他类型冠心病患者(P<0.01)。冠心病组产细胞毒素HP IgG阳性率(50.26%)与对照组(14.71%)比较差异显著。结论幽门螺杆菌感染与冠心病之间存在明显的相关性,不同毒力的HP感染与冠心病有统计学意义,即产细胞毒素HP IgG阳性与冠心病存在相关关系。
作者 乔竹风 洪阳 周力
机构地区 贵阳医学院附属医院消化科
出处 《海南医学》 CAS 2010年第3期38-40,共3页 Hainan Medical Journal
关键词 冠心病 幽门螺杆菌 相关性
分类号 R541.4 [医药卫生—心血管疾病]
  • 相关文献

参考文献7

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二级参考文献8

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共引文献5

同被引文献43

引证文献7

二级引证文献35

海南医学
2010年 第3期

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