摘要
在高血压的循证治疗中,始终存在着相矛盾的临床证据。人群调查显示,血压越低心血管病危险越少。因此,不少学者坚信,在患者耐受的情况下,应力争最大限度地降低血压。也有一些临床研究证实,血压降到一定程度后,反而增加心血管事件的危险,出现所谓的J形曲线。本文回顾性综述上述两种观点近几年的临床研究证据,为正确认识这些研究结果,制定科学合理的血压管理策略提供依据。
In antihypertensive treatment, sometimes the clinical evidence conflicts each other. Some investigation data showed the lower blood pressure the lower risk of cardiovascular disease. However, the other clinical data confirmed that the risk of cardiovascular disease could increase when blood pressure declines to certain degree which is so-called J-curve. This review provided a basis for rational medication based on both two clinical evidences recently.
出处
《世界临床药物》
CAS
2010年第1期44-47,60,共5页
World Clinical Drug
关键词
降压治疗
J形曲线
高血压
死亡率
antihypertensive treatment
J-curve
hypertension
mortality
