摘要
从中性粒细胞(PMN)和绵养红细胞自然形成E花环的能力证实PMN表面存在E受体。正常成人PMN-E花环形成百分率为31。97±5.71((?)±SD)。用T淋巴细胞E受体的单克隆抗体(anti-CCT_3)进行花环形成抑制试验,证明PMN和T淋巴细胞的E受体在抗原性方面是不同的。恶性肿瘤病人PMN-E花环形成能力较正常人明显下降(P<0.01),可能与患者抵抗力下降有关。
The ability of PMN and SRBC to form E-rosette naturally proved that PMN had E receptor (ER). The percentage of PMN-E rosette formation was 31.97±5.71 (±SD) in healthy persons. Using the McAb (anti-CCT) of the ER of T lymphocyte, the results of rosette formation inhibiting assay proved that the ERs of PMN and T lymphocyte were different in antigenicity. The ability of PMN-E rosette formation in the tumor patients reduced markedly (P<0.01), which may be related to the weakened resistance of the patients.
出处
《南通医学院学报》
1990年第4期285-286,351,共2页
ACTA Academiae Medicinae Nantong
关键词
中性粒细胞
E受体
淋巴细胞
PMN
E-rosette formation
lymphocyte
E receptor
