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成人急性非淋巴细胞性白血病未完全缓解40例临床分析

CLINICAL ANALYSIS OF 40 UNREMITTED PATIENTS WITH ACUTE NON-LYMPHOBLASTIC LEUKEMIA
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摘要 本文对40例成人急性非淋巴细胞性白血病(ANLL)用HOAP方案后未获完全缓解病例的治疗结果,按Pre is le r分型标准进行分型和分析。并探讨未缓解的原因,从而提出相应改进措施,以达到提高ANLL缓解(CR)率、延长生存期的目的。未缓解(NR)病例中,Ⅰ~Ⅱ型22例占55%,原因是患者具有不同程度的抗药性;而Ⅳ~Ⅴ型9例,其中早幼粒细胞性白血病(M_3)占7例,它是早期死亡最多的一类。 Forty unremitted patients with acute nonlymphoblastic leukemia (ANLL)after HOAP therapy were studied. Five groups were classified and analysed according to Preisler's standards for assessing the causes of unremission. In order to enhance the remission rate of ANLL and to extend survival duration,a new measurement was advanced. The majority of unremitted patients were in groups Ⅰ and Ⅱ(55%). Failure in remission was considered as resistant to chemotherapy in a different degree. 7 of the 9 cases in the groups IV and V were M_3 type, which has the highest death rate in early stage among subtypes of ANLL.
出处 《南通医学院学报》 1990年第2期117-119,176,共3页 ACTA Academiae Medicinae Nantong
关键词 白血病 ANLL 抗药性 成人 缓解 leukemia remission resistant disease
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