摘要
本文报道我院33例急性非淋巴细胞性白血病(ANLL)用HOAP方案经诱导缓解后的生存情况。生存3年22例,3年以上5例,5年以上6例。目前存活4例,中数缓解期12月,中数生存期18月,其中最长存活时间110月。并分析了影响长期生存的有关因素,初步认为缓解后维持治疗似无必要。提出中医中药、免疫治疗、加强心理护理,借以保护正常的免疫机能是提高ANLL缓解期、延长生存期所必需的。
The survival after the induction of complete remission (CR) with HOAP chemotherapeutic remedy was studied in 33 patients with acute nonlymphocytic leukemia (ANLL). Twenty-two patients survived for less than 3 years and 11,more than 3 years. Six patients survived for more than 5 years, and among them 4 are alive up to present time. Median CR duration was 12 months.Median survival duration was 18 months, and the longest survival was 110 months. Having analyzed the factors affecting survival, we found that survival duration was correlative to white blood cell counts at diagnosis, centralnervous system leukemia and DIC during induction therapy (P<0.05) but not o the enlargement of liver, spleen and lymph nodes, cellularity and blast percentage of bone marrow, courses of induction treatment or dosage of drugs (P>0.05). The observation on 6 cases of longer survival suggested that the maintenance therapy may be unnecessary in ANLL. The traditional Chinese medicine, immunotherapy and psychosomatic therapy which could protect normal immunity were important to prolong CR and survival duration.
出处
《南通医学院学报》
1990年第2期115-116,130,共3页
ACTA Academiae Medicinae Nantong
关键词
白血病
ANLL
缓解
acute nonlymphocytic leakemia
long survival
complete remission
