摘要
测定某强制戒毒所戒断９１ｄ±ｓ５．６ｄ的３１名男性海洛因依赖者的性激素水平，并做精液常规和生化分析，同吸毒组和正常对照组作比较，结果表明戒断治疗三个月的男性海洛因依赖者下丘脑－垂体－性腺轴的分泌调节功能紊乱已基本恢复，睾丸生精功能亦基本恢复，但附属性腺功能尚未恢复，表现在精液总量和精子活率仍低，精浆微量元素Ｚｎ、Ｃｕ、Ｃａ、Ｆｅ的改变尚未恢复，仅精浆果糖浓度同正常对照差异无显著性（Ｐ＞０．０５）。
Gonadal function was investigated in 31 young males who had been treated for heroin dependence about three months (91 d±s 5.6 d) by measuring basal serum concentration of follicle stimulating hormone (FSH), luteinizing hormone (LH),prolactin (PRL) and testoterone (T). Semen analyses were also undertaken in all subjects. The results were compared with those of the normal control group(n=30) and the heroin addictive group (n=30). There were no significant differences in the mean age of the three groups (P>0.05). Meanwhile, there were no significant differences in the amount of heroin abused between the addictive group and the abstinent group either. The results showed that PRL and LH in the serum of heroin abstinent group were no longer different from those of the control group (P>0.05), but T was significantly higher than that of the control group (P<0.01). The spermatogenic function of the seminiferous tubules had recovered. However, the function of the accessory glands had not recovered yet. For the heroin abstinent groups revealed that the asthenozoospermia and mean semen amount was lower than that of the control group. Regarding the alterations of the trace elements Zn, Cu, Ca and Fe in semen of the heroin abstinent group had not recovered either. Only the fructose concentration in sperm presented the same as that of with the control group (P>0.05).
出处
《中国药物依赖性杂志》
CAS
CSCD
1998年第4期205-209,共5页
Chinese Journal of Drug Dependence
基金
云南省卫生厅资助
关键词
海洛因依赖
戒断
性腺轴功能
精液
微量元素
heroin dependence
abstinence
spermatogeny
spermatic trace element
hypothalamic-pituitary-testicular axis
