摘要
对325例不同胃部疾患者的胃粘膜活检材料进行CP镜检和脲酶活性测定,结果证明幽门弯曲杆菌是胃部疾患的常见细菌,特别是慢性活动性胃炎CP的阳性率高达89％,脲酶活性升高达90％,进而用能杀灭CP的铋制剂对CP阳性(+++++)且脲酶活性阳性(10min内显反应)的慢性活动性胃炎患者进行治疗,在一个疗程后症状明显减轻或消失,此时镜检CP阳性率和脲酶活性均明显下降。就每一病例而言,CP的减少和脲酶活性的下降完全一致,因此建议用简便易行的脲酶活性检查代替CP镜检,这在胃部疾患的CP研究中是适宜的。
Reported here are the results of microscopic examination of Campylobacter pyloridis(CP) and the tests of urease activity in the biopsy of gastric mucosa from 325 patients suffering from different gastropathies. The results suggested that CP was the common bacteria present in gastropathy, especially in active chronic gastritis in which the positivity rates of CP and urease were as high as 89% and 90% respectively. 40 active chronic gastritis patients whose CP and urease activity were strongly positive were treated with the CP bactericidal drug bisuc. After one course of treatment the symptoms subsided or disappcared and the CP positivity rates and urease activities markedly reduced simultaneously. These results supported the idea that CP might be the cause of chronic gastritis. Being much simpler than the microscopic examination of CP the urease activity test is recommended to replace the microscopic examination of CP.
关键词
幽门弯曲杆菌
脲酶
胃炎
campylobacter
pylorus
urease
stomach diseases
