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中医方药量-效关系科学问题的探讨 被引量:21

An Exploration into Dose-Effect Relationship of Chinese Drug Prescriptions
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摘要 中医方药存在着与功效相关的量的规定性。在不同的组方配伍中,各个药物有不同的用量范围,共同发挥相辅相成或相反相成的综合作用。与证候相关是中医方药别于化学药的特征表现,也是形成中医方药量效关系的基础条件。方药临床疗效是方药效应成分群与机体相互作用表现出的整合效应。经典方剂存在量效关系,具有双相二时段基本特征(双相是指证候转归取效和疾病指证取效的双相性特征;二时段是指用药过程中表现出的与双相性效应相对应的两阶段时效性特征)和病证-结构-剂量-物质-功效五要素关联规律。 There is a dose - effect relationship in Chinese drug prescriptions. With different combination of drugs in the prescription, the dodge of each drug varies, and the drugs in combination supplement or counteract each other. One of the differences between Chinese drugs and chemical drugs is the fact that Chinese medicine pays attention to the syndromes, which is also the basis for the dose- effect relationship in Chinese drug presefiptions. The effect of Chinese drug prescriptions is the manifestation of the interaction between compo- nents and the human body. The authors put forward the view that there exists dose- effect relationship in classical prescriptions, i. e. the two- phase two- period characteristics (the former refen'ing to effect on syndromes and effect on diseases;the latter referring to the two period of time of effectiveness corresponding to the two phases), and the five - element ( disease, structure, dosage, substance, efficacy)correlation regularity.
出处 《南京中医药大学学报》 CAS CSCD 北大核心 2010年第1期1-6,共6页 Journal of Nanjing University of Traditional Chinese Medicine
基金 江苏省高校自然科学重大基础研究项目(06KJA36022) 江苏省"青蓝工程"科技创新团队建设项目资助(2006)
关键词 中医 方药 量效关系 研究模式 基本特征 双相二时段 Chinese medicine drug prescription dose - effect relationship research mode basic characteristics two - phase two - period characteristics
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