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不同延期神经再支配环杓后肌方法的疗效观察

EFFECT OBSERVATION OF DIFFERENT DELAYED REINNERVATION OF POSTERIOR CRICOARYTENOID MUSCLE
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摘要 目的:探讨环杓后肌延期神经再支配的方法及时机。方法:将29只狗分成三组,两个实验组在喉返神经切断后即刻、4、6、8、10、12个月分别将膈神经与喉返神经吻合选择性支配环杓后肌和颈袢神经—胸骨甲状肌蒂植入环杓后肌,对照组喉返神经切断后各时间不作任何手术。结果:两个实验组6个月后行喉镜、神经肌电及肌收缩力、组织化学证实:神经吻合组各时间效果明显好于神经肌蒂植入组,但两种术式疗效均随病程延长而下降。结论:神经吻合法延期神经再支配环杓后肌6个月内效果较好,而神经肌蒂植入法治疗环杓后肌麻痹最好不晚于失神经后4个月。 Objective:To investigate methods and time of delayed reinnervation of the posterior crocoarytenoid muscle (PCA).Methods:29 dogs were divided into three groups.24 dogs in the two experimental groups were reinnervated at 0,4,6,8,10 and 12 month interval following recurrent laryngeal nerve cut via the phrinic nerve anastomosed to the recurrent laryngeal nerve after cutting the adductor branch and ansa cervicalis sterothyroid muscle pedicle implanted into the posterior cricoarytenoid muscle.5 dogs in the control group were not reinnervated after recurrent laryngeal nerve cut.Laryngoscopies,electromyography,contractile tension of posterior cricoarytenoid muscle and histologic studies were performed six months after operation.Results:The effect was better in the nerve anastomosed group than in the nerve muscle pedicle group,but the effect decreased gradually with the increase of the denervation time.Conclusion:The effect will be good if delayed reinnervation with nerve anastomosed method is performed within six months after denervation,but not good if delayed reinnervation with nerve muscle pedicle implanted method is performed over four months after denervation.
出处 《中国耳鼻咽喉颅底外科杂志》 CAS 1998年第3期133-137,共5页 Chinese Journal of Otorhinolaryngology-skull Base Surgery
关键词 喉返神经麻痹 神经再支配 环杓后肌 Recurrent laryngeal nerve Paralysis Reinnervation Posterior cricoarytenoid muscle Dogs
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