摘要
目的研究新生儿感染性肺炎的病原和临床表现。方法用间接免疫荧光法检测呼吸道合胞病毒、腺病毒、流感和副流感病毒,部分患儿进行了巨细胞病毒、柯萨奇病毒、解脲支原体和人型支原体血清学检查。结果165例新生儿肺炎中呼吸道病毒阳性44例(26.7%),疑似病毒肺炎27例(16.4%),疑似支原体肺炎4例(2.4%),临床诊断细菌肺炎11例(6.7%),不明原因肺炎79例(47.9%)。对呼吸道合胞病毒肺炎、腺病毒肺炎和细菌肺炎的临床表现进行了分析。结论本次调查新生儿肺炎病原以病毒多见,新生儿肺炎临床症状不典型,难以依靠临床表现作出病原学诊断。
Objective To study the aetiology and clinical manifestation of neonatal pneumonia. Methods Respiratory syncytial virus (RSV), adenovirus (ADV), influenza virus (IFV) and parainfluenza virus (PIV) of nasopharyngeal secretion were detected in all cases and cytomegalovirus, coxsackie B virus and mycoplasma were detected in most of the neonatal cases by immunofluorescence. Results Among 165 newborn pneumonia cases, 44 were positive for viruses, including 27 for RSV (16.4%), 15 for ADV (9.1%) and 2 for PIV Ⅲ (1.2%), 27 were suspected to be viral pneumonia (16.4%), 4 mycoplasma pneumonia (2.4%) 11 were clinically diagnosed as bacterial pneumonia (6.7%) and 79 were classified as caused by unclear pathogens (47.9%). The authors especially analysed manifestations of respiratory syncytial virus, adenovirus and bacterial pneumonia. Conclusion Virus is the most common agent for newborn pneumonia and aetiology diagnosis of newborn pneumonia cannot be presumed only by clinical manifestations.
出处
《中华儿科杂志》
CAS
CSCD
北大核心
1998年第10期601-603,共3页
Chinese Journal of Pediatrics
关键词
新生儿肺炎
病原学
临床表现
Infant, newborn Pneumonia,viral Pneumonia, bacterial