摘要
目的 研究低治疗量碘化钾对孢子丝菌病发病的影响 ,为预防本病提供理论依据。方法采用含碘化钾的饮水饲养实验鼠 ,并设对照组 ,2周后行腹腔接种孢子丝菌 ,于接种后的第 3～ 8周 ,每周分批处死实验鼠 ,剖检 ,观察发病情况、病理学改变及真菌学所见。结果 实验鼠本病的发病率显著下降 (P <0 0 1) ,其下降与碘化钾的用量有关。结论 低治疗量碘化钾具有预防孢子丝菌病发病的作用。
Objective To investigate the effect of potassium iodide on the incidence of sporotrichosis, and provide the theoretical basis for the prevention of sporotrichosis. Methods Experimental mice were divided into 4 groups, group 1～3 were fed with water containing different doses of potassium iodide, and no potassium iodide was given to the control group. After two weeks, the fungi were inoculated intraperitoneally to all the mice. In the third to the eighth weeks, the mice were sacrificed every week in batches. The infection, pathological changes and mycological findings of the mice were observed. Results The incidence rate of experimental sporotrichosis was significantly decreased in the mice (P<0 01), and the decrease was related to the dosage of potassimu iodide. Conclusion The results show that potassium iodide may be of use in the prevention of sporotrichosis.
出处
《中华皮肤科杂志》
CAS
CSCD
北大核心
1998年第5期300-301,共2页
Chinese Journal of Dermatology
基金
中华医学会皮肤科学会科研基金
关键词
孢子丝菌病
碘化钾
预防
Sporotrichosis Potassium Iodide Prevention Experimental animal
