摘要
目的探讨羟苄羟麻黄碱治疗先兆早产的临床疗效。方法研究对象随机分为麻黄碱组和硫酸镁对照组(n=36),观察两组有效抑制宫缩的显效时间、延长孕期、累积用药时间和药物副反应。结果治疗组与对照组比较:宫缩抑制显效时间([2.12±0.52)hvs(6.73±0.91)h]、累积用药时间([8.03±1.27)dvs(13.07±3.38)d]、延长孕期时间([25.64±5.36)dvs(15.37±4.85)d]、早产发生率(11.1%vs36.1%),差异有显著性(P<0.05)。结论羟苄羟麻黄碱治疗先兆早产安全有效,是治疗先兆早产较理想的药物。
Objective To investigate the chnical efficacy of hydroxyl benzyl ephedrine in the treatment of threatened premature. Methods Subjects were randomly divided into the treatment group and control group (n=36 ). The markedly inhibited uterine contraction time, the extension of pregnancy,the cumulative medication time and drug toxicity were observed in the two groups. Results A comparison between treatment group and control group showed the onset time of the inhibited uterine contraction was(2.12 ± 0.52)h vs (6.73 ± 0.91 )h,the cumulative medication time was(8.03 ± 1.27)d vs ( 13.07 ± 3.38)d,the extended pregnancy time was(25.64 ± 5.36)d vs ( 15.37 ± 4.85)d and the incidence of prematurity was 11.1% vs 36.1% (all P〈0.05). Conclusion Hydroxyl hydroxyl benzyl ephedrine is effective and feasible in the treatment of threatened premature delivery.
出处
《中国现代医生》
2010年第1期43-44,共2页
China Modern Doctor
关键词
先兆早产
羟苄羟麻黄碱
疗效评价
Threatened preterm labor
Hydroxyl hydroxyl benzyl ephedrine
Evaluation