摘要
目的观察血浆置换治疗肝衰竭患者的疗效。方法30例肝衰竭患者在内科综合治疗基础上进行血浆置换治疗,观察血浆置换前后肝肾功能、凝血功能的变化。结果治疗后患者的血清总胆红素、直接胆红素、转氨酶降低(P<0.01),血清白蛋白水平升高(P<0.01),凝血酶原时间缩短(P<0.01)。早期肝衰竭患者治疗有效率为91.67%,中期患者有效率为50%,晚期患者均无效死亡。结论血浆置换是一种有效的治疗方法,能缓解肝衰竭患者的病情,获得病情恢复时间。血浆置换进行得越早,疗效相对越好。
Objective To observe the efficacy of plasma exchange in treatment of patients with liver failure. Methods Besides the internal supporting treatment, patients with liver failure were also treated with plasma exchange. Liver function,renal function and prothrombin time were examined pre-and post-plasma exchange. Results After plasma exchange, patients had significant improvements in total serum bilirubin, direct bilirubin, serum albumin and prothrombin time （P 〈 0.01）. The clinical efficacy rate of the patients with liver failure in early, middle and end stage was 91.67%, 50% and zero respectively. Conclusions Plasma exchange can effectively improve liver function and prothrombin time, and is an effective treatment for patients with liver failure. The earlier plasma exchange treatment, the better efficacy.
出处
《北京医学》
CAS
2010年第1期19-21,共3页
Beijing Medical Journal
关键词
肝衰竭
血浆置换
疗效
Liver failure
Plasma exchange
Efficacy
