摘要
目的探讨血小板数与脾大小之比、血清-腹水白蛋白梯度和肝硬化食管静脉曲张的关系。方法对101例肝硬化合并腹水者进行生化检测、腹部B超、胃镜检查,分析食管静脉曲张与脾长、脾厚、脾大小(长×厚)、门静脉及脾静脉直径、血小板数、血小板数与脾大小之比及血清-腹水白蛋白梯度的关系。结果食管静脉曲张组血小板数与脾大小之比为1.4±1.0,其血清-腹水白蛋白梯度为(24.1±10.4)g/L,无食管静脉曲张组血小板数与脾大小之比为1.9±0.9,其血清-腹水白蛋白梯度为(14.4±8.3)g/L,两者比较有显著性差异,经Logistic回归分析其可预测食管静脉曲张的发生。结论当内镜不能顺利实施时,血小板数与脾大小之比及血清-腹水白蛋白梯度可作为预测食管静脉曲张的一种经济、无创的手段。
Objective To study the value of platelet count to spleen sizes ratio and serum-ascites album gradient （SSAG） as a noninvasive parameter for diagnosing esophageal varices （EV） in liver cirrhosis. Methods The laboratory and uhrasonographic variables were prospectively evaluated in 101 patients with liver cirrhosis. All patients underwent upper gastrointestinal endoscopy. Results The platelet count to spleen sizes ratio and SSAG in patients with EV were 1.4±1.0 and 24.1±10.4 g/L. The platelet count to spleen sizes ratio and SSAG in patients without EV were 1.9±0.9 and 14.4±8.3 g/L. There was significant difference between patients with and without EV. The platelet count to spleen sizes ratio and SSAG had the highest accuracy among all parameters and they could predict the presence of esophageal varices in liver cirrhosis . Conclusions The platelet count to spleen sizes ratio and SSAG may be a useful tool for diagnosing EV in liver cirrhosis noninvasively when endoscopy facilities are not available.
出处
《北京医学》
CAS
2010年第1期16-18,共3页
Beijing Medical Journal
关键词
血小板数与脾大小之比
血清-腹水白蛋白梯度
食管静脉曲张
肝硬化
Platelet count to spleen diameter ratio
Serum-ascites album gradient （SSAG）
Esophageal varices（EV）
Liver cirrhosis
