摘要
选择山东、上海４个工厂共计５８７５位工人为研究对象，采用回顾性队列研究的方法探讨了甲醛暴露与胃癌发病之间的关系，结果表明：接触甲醛组胃癌的发病率（９７．１３／１０万）显著高于非接触组（３３．４６／１０万），Ｐ＜０．０１，相对危险度为２．９０。用Ｐｏｉｓｓｏｎ回归调整性别、年龄、吸烟、饮酒、接触年限等变量后，其差异仍具有显著性（Ｐ＜０．００１），相对危险度为３．２８。研究表明，甲醛可能是引起胃癌发病的危险因素之一。
Formaldehyde being carcinogen substance to animal has no adequate evidence in human beings.Especially,people has very few study on the relationship between occupational exposure to formaldehyde and gastric cancer.A retrospective cohort study using 5 875 persons from 4 factories was applied to investigate the relationship between exposing to formaldehyde and gastric cancer.It showed that incidence of the gastric cancer in the exposed group(97.13 per hundred thousand)was significant higher than that in the unexposed group(33.46 per hundred thousand)P<0.01.And relative risk(RR) was 2.90.After people adjusting sex,age,smoking,alcohol drinking etc.by poisson regression,there was also a significant difference between the two groups(P<0.001,RR was 3.28).So it can be concluded that exposing to formaldehyde may be a risk factor of gastric cancer incidence.
出处
《中国慢性病预防与控制》
CAS
1998年第4期175-176,204,共3页
Chinese Journal of Prevention and Control of Chronic Diseases
基金
山东省科研基金
