摘要
目的：探讨冬虫夏草治疗慢性呼吸衰竭（呼衰）的作用机制。方法：对３０例肺源性心脏病（肺心病）呼衰患者在综合治疗的基础上采用冬虫夏草治疗，治疗前后进行血浆氨基酸测定并比较其变化。结果：应用冬虫夏草后除苯丙氨酸外的人体必需氨基酸均增高，患者的支链氨基酸／芳香族氨基酸（ＢＣＡＡ／ＡＡＡ）比值明显上升。结论：冬虫夏草是通过改变血浆氨基酸，使ＢＣＡＡ／ＡＡＡ比值上升，而对肺心病呼衰发挥辅助治疗作用的。
Objective:To explore the mechanism of Dongchong Xiacao treating chronic respiratory failure (RF).Methods:Thirty cases of RF with corpulmonale were treated with Dongchong Xiacao on the basis of complex treatment,then,to detect the amino acid level and compare the changes between before and after treatment.Results:After therapy with Dongchong Xiacao,all essential amino acid level were raised except phenylalanine,the ratio of branched chain amino acids (BCAA) with aromatic amino acid (AAA) was increased obviously.Conclusions:Dongchong Xiacao can treat assistantly RF with corpulmonale through changing plasma amino acid level and raising the ratio of BCAA with AAA.
关键词
冬虫夏草
呼吸衰竭
肺心病
治疗
血浆支链氨基酸
Dongchong Xiacao\ \ corpulmonale\ \ respiratory failure\ \ plasma branched chain amino acids\ \ plasma aromatic amino acid
