摘要
目的观察六联强化加序贯治疗对老年骨质疏松症合并骨关节炎患者的疗效,并探讨机理。方法对患者采用早期强化,后期序贯治疗的方法。即早期使用透明质酸钠关节内注射,鲑鱼降钙素注射,鹿瓜多肽静滴,后期使用鲑鱼降钙素喷鼻、骨化三醇、中药骨疏灵口服等治疗,分别观察对疼痛评分,关节功能,拐杖使用情况,骨密度,血液及关节液生化指标等进行观察,并设对照组。结果治疗后发现患者疼痛及关节功能障碍迅速缓解,拐杖等使用情况好转,血液生化指标改善,关节炎性指标降低,骨密度显著提高,并与对照组比较差异有显著性。结论六种药物相互配合,中西结合,内外并用,标本兼治是治疗骨关节炎的有效方法,而保护软骨,抗炎,补肾壮骨是其机理。
Objective To observe the effects of six medicines with intensive ＆ sequential therapy on aged osteoporosis osteoarthritis. Methods Intensive therapy with Hyluronan Gel, Salcatonin injection and Lugua Polypeptide Injection were used at early two weeks, serial therapy with Caleitriol pill, Salcatonin Nasal Spray, and Gushuling compounds were used at following ten weeks. Some items such as pain＇s Numerical rating scale, joint＇s functional assessment, stick＇s using state, blood biochemical item and bone density, etc were observed. Results The patient＇s pains, joint＇s function were relieved rapidly; stick＇s using amount and frequency were decreased too. The bone density and blood biochemical items were improved and the difference was significant compared with the control group（ P 〈 0.05-0.01 ）. Conclusion The combined medicines which were both western medicine and traditional Chinese medicine, and combined therapy which was given oral and injection was effective and rapid ways to treat osteoporosis osteoarthritis.
出处
《中国骨质疏松杂志》
CAS
CSCD
2009年第12期908-912,共5页
Chinese Journal of Osteoporosis
关键词
强化治疗
序贯治疗
骨关节炎
骨质疏松症
Intensive therapy
Sequential therapy
Osteoarthritis
Osteoporosis
