摘要
80年代以来已在脊髓背角鉴定出10种以上新的感觉投射神经元。所有这些神经元均以其分支的轴突或侧支轴突为特征。这些神经元的分支轴突分别向两个以上的不同核团,包括体感核和内脏感觉核投射。其中有些神经元从其所投射的中枢靶核接受躯体与内脏的传入输入,同时通过分叉初级传入从外周接受躯体与内脏的传入输入。有些外周感觉输入可首先在脊神经节神经元上会聚并被加工处理。这些发现看来是对感觉神经元单投射与单支配的传统观念的挑战并参与躯体内脏相关和有关的临床障碍。
Ten or more types of sensory projection neurons have been identified in the spinal dorsal horn since the 1980s. All these novel populations of neurons are characterized by their branched or collateral axcons projecting to two or more distinct target nuclei, including somatosensory and viscerosensory nuclei. Some of these neurons receive afferent inputs including somatic and visceral sensory inputs, in turn, from their central targets and from the periphery via dichotomized primary afferents. Some peripheral sensory inputs may first converge on and be processed by dorsal root ganglion neurons. These findings seem to challenge the traditional Concept of single projections and innervation of sensory neurons and to be involved in the mechanisms underlying somatovisceral interaction and related clinical disorders.
出处
《神经解剖学杂志》
CAS
CSCD
北大核心
1998年第3期294-302,共9页
Chinese Journal of Neuroanatomy
关键词
轴突分叉
躯体内脏相关
脊髓背角
脊神经节
branched or collateral axcons, dichotomized primary afferents, somatovisceral sensory convergence, somatovisceral integration, spinal dorsal horn, dorsal root ganglion