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保乳手术确定标本边缘的探讨 被引量:2

Discussion on the surgical margin of breast-conserving surgery
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摘要 目的探讨保留乳房的乳腺癌切除术如何确定标本边缘。方法选择符合保留乳房标准的乳腺癌111例,实施保乳手术,手术标本边缘按照肿瘤周围1cm正常组织切除。术后根据病理、临床分期制定个体化的综合治疗,定期随访患者局部和全身情况。结果111例乳腺癌符合保乳手术治疗标准,实施了保乳手术治疗并能接受定期随访,1例出现局部区域复发。结论按照肿瘤周围1cm正常组织切除,取其左、右、上、下、基底5个面作冰冻切片,证实标本边缘无肿瘤浸润。绝大多数患者可获满意的美容效果,提高了早期乳腺癌患者的生存质量。 Objective To discuss how to determine the operative margin in breast-conserving surgery in patient with early-stage breast cancer. Methods The breast-conserving surgery was performed on 111 patients with early-stage breast cancer who met the indication of breast-conserving. The operative incision was performed on normal breast tissue 1 cm from the turnout edge and then the frozen sections of the surgical margin tissue were done to confirm that tumour was completely excised. The individualized therapy was performed according to pathologic examination and clinical stage. All patients were followed up regularly. Results 111 patients with early stage breast cancer received breast-conserving surgery and all had good curative effect except one patient had a local recurrence during the follow-up. Conclusions Operative incision on normal breast tissue 1 cm from the turnout edge and frozen section of the surgical margin tissue are two crucial procedures to ensure the success of breast-conserving surgery and increase the life quality of patient with breast cancer.
出处 《中华内分泌外科杂志》 CAS 2009年第6期378-380,共3页 Chinese Journal of Endocrine Surgery
关键词 乳腺癌 保乳手术 标本切缘 Breast cancer Breast-conserving surgery Surgical margin
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  • 2Veronesi U, Cascinelli N, Mariani L, et al. Twenty year follow- up of a randomized study comparing breast cancer-conserving surgery with radical mastectomy for early breast cancer [J]. N Engl J Med, 2002,347(16) : 1227-1232.
  • 3Yasuo H, Hirotaka I, Toyama T, et, al. Telomerase activity levels for evaluating the surgical margin in breast-conserving surgery[J]. Surg Today, 2001,31 (4) : 289-294.
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  • 5Fisher 13. Lumpectomy(segmental mastectomy) and axillary dissection. In: Bland KI, Copeland EM (eds). The breast: Comprehensive management of benign and malignant diseases. Vol. 2,2th FAition, Saunders[J]. Philadelphia. 1998 : 917-939.
  • 6Pleijhuis R G. Graafland M, de Vries J. et al.Obtaining adequate surgicalmargins in breast-conserving therapy for patients withearly-stage breast cancer: currentmodalities and future direc-tions[J]. Ann Surg Oncol, 2009, 16(10): 2717.
  • 7Jacobs L. Positive margins: the challenge continues for breastsurgeons[J].Ann Surg Oncol, 2008, 15(7): 1271.
  • 8武正炎,王水,刘晓安,查小明,肖秀娣,李海志,斯岩,陶爱娣.乳腺癌保乳手术切除范围的探讨[J].中华普通外科杂志,2011,26(10):833-836. 被引量:18
  • 9肖秀娣,赵远,陆莉,陈培勤,虞浩,徐雪松,武正炎.乳腺癌保乳手术后局部复发的原因分析[J].江苏医药,2012,38(19):2308-2309. 被引量:4
  • 10张保宁,余子豪.乳腺癌保乳手术的几个关键问题[J].中华肿瘤杂志,2001,23(6):523-524. 被引量:107

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