摘要
目的研究Bcl2、Bax在卵巢子宫内膜异位囊肿中的表达及临床意义。方法应用免疫组织化学方法对研究组39例卵巢子宫内膜异位囊肿患者的在位子宫内膜及异位子宫内膜及对照组27例正常子宫内膜进行Bcl2、Bax检测。结果Bcl2、Bax在卵巢子宫内膜异位囊肿患者的异位内膜与在位子宫内膜中的表达差异有统计学意义(P<0.05);在异位内膜、在位内膜与正常内膜中的表达差异有统计学意义(P<0.05);Bcl2、Bax在卵巢子宫内膜异位囊肿中的表达呈负相关趋势,差异有统计学意义(P<0.05)。结论Bcl2表达增强、Bax表达减弱可能与子宫内膜异位症的发生、发展有关。
Objective To study the expression and clinical significance of Bcl2 and Bax in ovarian endometriosis.Methods Immunohistochemistry methods was employed to detect the expression of Bcl2 and Bax in the ectopic and eutopic endometrium of the patients （39 cases） with endometrisis,and in the nomal endometrium （27cases） in the contral group.Results The expression of Bcl2 and Bax was significant difference to ectopic endimetrium and eutopic endimetrium of ovarian endometriosis （P0.05） and there was significant difference between the study group and control group （P0.05）,and the expressions of Bcl2 and Bax in ovarian endometriosis were negative correlated.Conclusion The increasing expression of Bcl2 and decreasing of Bax may play the key role in occurrence of endometriosis and adenomyosis.
出处
《宁夏医学杂志》
CAS
2009年第12期1143-1144,F0003,共3页
Ningxia Medical Journal
基金
2006年宁夏医科大学面上项目支持
