摘要
目的评价针刺治疗变应性鼻炎的疗效。方法对针刺治疗变应性鼻炎的随机对照试验(RCT)或半随机对照试验(CCT)按Cochrane协作网推荐的方法进行系统评价,并使用专用的统计分析软件RevMan4.2版进行Meta分析统计学处理。结果11批随机对照试验(RCT)或半随机对照试验(CCT)满足纳入标准,纳入人数范围从70~420人,共1733人,均为低质量试验。经Meta分析,纳入的11批试验结果表明了针刺治疗变应性鼻炎的疗效优于对照组[RR 1.23,95%CI(1.14,1.33),Z=5.15,P<0.00001]。结论虽然针刺治疗变应性鼻炎的疗效优于对照组,且无毒副反应,但由于纳入研究数量和质量上存在缺陷,因此开展更多高质量、内在真实性好的大规模、多中心的RCT研究非常必要。
Objective To assess the therapeutic effect of acupuncture on allergic rhinifis. Methods A systematic review including all the relevant randomized controlled trials (RCT or CCT )of acupuncture for treatment of allergic rhinitis were performed using the method recommended by the cochrane collaboration. The data were statistically analyzed with a special analysis software RevMan 4.2. Results Eleven experiments including randomized controlled trials (RCT or CCT ) met the enrolled criteria. The number of included persons ranged from 70 to 420 and totaled 1733. All of the trials were of lower methodological quality. Meta--analysis of enrolled 11 trials showed that the acupuncture group had a better therapeutic effect on allergic rhinitis than the control group(RR 1.23, 95%CI (1.14, 1.33 ) o Z =5.15, P〈0. 00001). Conclusion Although the acupuncture group had a better therapeutic effect on allergic rhinitis than the control group and without toxic side effects, but the included literatures on the study were not high quality studies. Therefore, it is necessary to perform more multi-central randomized controlled trials in good internal validity and high quality in future.
出处
《中国中西医结合耳鼻咽喉科杂志》
2009年第6期309-312,共4页
Chinese Journal of Otorhinolaryngology in Integrative Medicine
关键词
变应性鼻炎
针刺疗法
评价研究
Allergic rhinitis
Acupuncture therapy
Evaluation Studies