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受血者输血前检测IgA含量的临床价值 被引量：3

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摘要 目的通过检测受血者血液中免疫球蛋白A(IgA)的含量,探讨受血者IgA的含量与输血超敏反应的关系,以说明输血前检测受血者IgA的重要性。方法用速率散射免疫比浊法检测受血者输血前IgA的含量。分析IgA缺乏或低下受血者与IgA的含量正常受血者的输血超敏反应的发生率。结果1 578例受血者输血前IgA含量低于参考范围的有3例,占0.190%(3/1 578),其中1例为IgA完全缺乏,占0.063%(1/1 578);IgA缺乏或低下受血者组输血后均出现严重的输血超敏反应(100%,3/3),其输血超敏反应发生率明显高于IgA含量正常的受血者组(1.14%,18/1 575)(P<0.01)。1 578例血者中出现过敏性休克1例(0.063%,1/1 578)。结论IgA缺乏或低下的受血者输血后易出现严重的输血超敏反应。输血前检测受血者IgA的含量对于防范和减少输血超敏反应的发生,保证受血者的输血安全有重要意义。
作者 陈秉宇 梅梦寒 谢一唯
机构地区 浙江省人民医院输血科
出处 《检验医学》 CAS 北大核心 2009年第12期920-921,共2页 Laboratory Medicine
关键词 免疫球蛋白A 受血者 输血超敏反应 输血安全
分类号 R446.62 [医药卫生—诊断学]
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  • 1Mollison PL,Engelfriet CP,Contreras M.Blood transfusion in clinical medicine[M],Oxford: Blackwell Scientific Publications,1993:694
  • 2Muylle L,Beert JF,Mertens G,et al.Histamine synthesis by white cells during storage of platelet concentrates[J].Vox Sang,1998,74(3):193-197
  • 3Simon TL,Dzik WH,Snyder EL,et al.Rossi' s principles of transfusion medicine[M].Philadelphia:Lippincott Williames & Wakins,2002,837-840
  • 4Kluter H,Bubel S,Kirchner H,et al.Febrile and allergic transfusion reactions after the transfusion of white cell-poor platelet preparations[J].Transfusion,1999,39 (11-12):1179-1184
  • 5Lambin P,Le Pennec PY,Hauptmann C,et al.Advene transfusion reactions associated with a precipitating anti-C4 antibody of anti-Rodgers specificity[J].Vox Sang,1984,47(3):242-249
  • 6Beigamaachini L,Mannucci PM,Federici AB,et al.Posttransfusion anaphylactic reactions in a patient withsevere von Wille brand disease; role of complement and alloantibodies to von Willebrand factor[J].J Lab Clin Med,1995,125(3):348-355
  • 7Shimada E,Tadokoro K,Watanabe Y,et al.Anaphylactic transfusion reactions in haptoglobin-deficient patients with IgE and IgG haptoglobin antibodies[J].Transfusion,2002,42 (6):766-773
  • 8Hasegawa S,Pawankar R,Suzuki K,et al.Functional expression of the high affinity receptor for IgE (FcepsilonRI) in human platelets and its' intracellular expression in human megakaryocytes[J].Blood,1999,93(8); 2543-2551
  • 9Joseph M,Ameisen JC,Kusnierz JP,et al.Participation of the IgE receptor in the toxicity of blood platelets against schistosomes[J].CR Acad Sci Paris ffl,1984,298(3):55-60
  • 10Danese S,de la Motte C,Reyes BM,et al.Cutting edge:T cells trigger CD40-dependent platelet activation and granular RANTES release:a novel pathway for immune response amplification[J].J Immunol,2004,172(4):2011-2015

共引文献34

同被引文献31

  • 1肖淑芝.一例IgA缺乏症患者输血致过敏性休克的急救及护理[J].天津护理,2004,12(4):240-240. 被引量：4
  • 2Sandler SG,洪小珍.如何处理疑似IgA过敏性输血反应[J].国际输血及血液学杂志,2006,29(3):275-276. 被引量：7
  • 3Aghamohammadi A, Cheraghi T, Gharagozlou M, et al. IgA deficiency: correlation between clinical and immunological phenotypes. J Clin Immuno1,2009,29 ( 1 ) : 130-136.
  • 4Sandier SG. How I manage patients suspected of having had an lgA anaphylaetie transfusion reaction. Transfusion, 2006,46 ( 1 ) : 10- 13.
  • 5Sandier SG, Mallory D, Malamut D, et al. IgA anaphylactic transfusion reactions. Transfus Med Rev, 1995,9 ( 1 ) : 1-8.
  • 6Laschinger C, Shepherd FA, Naylor DH. Anti-IgA-mediated transfusion reactions in Canada. Can Med Assoc J, 1984,130 (2) : 141 - 144.
  • 7Clark JA, Callicoat PA, Brenner NA, et al. Selective IgA deficiency in Blood Donors. Am J Clin Pathol,1983,80(2) :210-213.
  • 8Kanoh T, Mizumoto T, Yasuda N, et al. Selective lgA deficiency in Japanese blood donors: frequency and statistical analysis. Vox Sang, 1986,50(2) :81-86.
  • 9Thibault L, Beausejour A, de Grandmont M J, et al. Establishment of an immunoglobulin A-deficient blood donor registry with a simple in-house screening enzyme-linked immunosorbent assay.Transfusion ,2006,46 (12) :2115-2121.
  • 10Chaudhary R, Chandran S, Khetan D, et al. Low prevalence of IgA deficiency in Indian population:a blood donor survey. Vox Sang, 2005,89( Suppl 1 ) :33.

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检验医学
2009年 第12期

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