摘要
目的：探讨经导管肝动脉化疗栓塞术（TACE）联合伽玛刀和射频热疗治疗原发性肝癌的临床价值。方法：56例原发性肝癌患者均先行TACE治疗1次，1周后应用体部伽玛刀治疗（中位剂量35Gy），同时配合射频热疗4～6次；其中有35例患者治疗结束2～3周后进行了第2次TACE治疗。随访终点为治疗结束后2年或患者死亡。结果：患者1、2年生存率分别为75．0％（42／56）和48．2％（27／56）。结论：TACE联合伽玛刀和射频热疗治疗原发性肝癌疗效确切、安全性较好，值得临床进一步探索。
Objective To investigate the clinical effect of transcatheter arterial chemoembolization （TACE） combined with γ-knife and radiofrequency hyperthermia in the treatment of primary hepatic cancer. Methods Fifty-six patients with primary hepatic cancer were studied. Whole body-γ-knife （stereotaetic radiotherapy, media dose 35 Gy） was performed a week after a TACE. Radiofrequency hyperthermia was administered for 4 -6 times during the radiotherapy. Thirty-five patients underwent a second TACE 2 -3 weeks after the above treatment. Then patients were followed up for 2 years or patients death. Results The 1,2-year survival rates in the patients were 75% （42/56） ,48.2% （27/56） ,respectively. Conclusion TACE combined with γ-knife and radiofrequency hyperthermia is effective in the treatment of primary hepatic cancer, better security and deserves further investigation.
出处
《东南大学学报（医学版）》
CAS
2009年第6期519-521,共3页
Journal of Southeast University(Medical Science Edition)
关键词
原发性肝癌
经导管肝动脉化疗栓塞术
伽玛刀
放射疗法
射频热疗
primary hepatic cancer
transcatheter arterial chemoembolization
γ-knife
radiotherapy
radiofrequency hyperthermia
