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急性心源性呼吸困难患者血浆BNP与心功能及预后的相关性分析

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摘要 目的探讨血浆B型钠尿肽(BNP)水平在判定急性心源性呼吸困难患者病情及预后中的价值。方法选取以急性心源性呼吸困难为主诉的患者127例,用免疫荧光法测定血浆BNP水平,同日测定左室舒张末期内径(LV)、左室射血分数(LVEF),随访住院期间及发病30、90 d的主要心脏不良事件(MACE),采用直线相关及多元Logistic逐步回归分析血浆BNP水平与LV、LVEF及MACE的相关性。结果血浆BNP水平与患者年龄、LV呈正相关,与LVEF呈负相关(P均<0.05);BNP水平是独立于年龄、LVEF等危险因素之外的心功能不全预后因素,其与30 d和90 d的MACE发生率均呈显著正相关(r=0.674、0.787,P<0.01)。结论根据血浆BNP水平可对急性心源性呼吸困难患者进行危险分层及预后判断。
出处 《山东医药》 CAS 北大核心 2009年第47期95-96,共2页 Shandong Medical Journal
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参考文献7

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