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原发性肝癌组织内Fas抗原的表达及其与肝动脉化疗栓塞的关系

The expressions of Fas Antigen in primary hepatocelluar carcinoma tissue and its relationship with TACE treatment
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摘要 为研究肝动脉化疗栓塞(TACE)治疗原发性肝癌的机制,通过对肝癌组织进行免疫组化研究,发现TACE治疗后肝癌组织内Fas抗原表达明显增强,其中Fas抗原阳性者αFP平均下降率明显高于Fas抗原阴性者,且术后复发时间明显延长。结果表明,TACE治疗效果可部分归因于TACE治疗后肝癌组织内Fas抗原表达的增加。 To evaluate the influence of transcathater arterial chemoembolization on the PHC, byusing immunohistochewical study, we found that the expression of Fas antigen in the tissue of PHC waspromoted, in Fas positive patients, the decrement of aFP level was greater, and the mean time of recurrence was prolonged significantly. The result showed that the increasement of Fas antigen expression afterTACE can improve the prognosis of PHC patients.
出处 《临床外科杂志》 1998年第5期256-257,共2页 Journal of Clinical Surgery
关键词 原发性 肝细胞性肝癌 肝癌 FAS抗原 TACE Primary hepatocelluar carcinorna Transcathater arterial chemoemblizationFas antigen Apoptosis
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