摘要
目的探讨高血压对胸主动脉解剖与功能的影响。方法应用多平面经食管超声技术，测量了正常组４１例和高血压组２２例受试者胸主动脉舒张期内径（Ｄｄ）、收缩期内径（Ｄｓ）、内膜———中层厚度（ＩＭＴ），计算了Ｐｅｔｅｒｓｏｎ’ｓ弹性指数（Ｅｐ）、Ｙｏｕｎｇ’ｓ弹性的指数（Ｅｓ）和僵硬度（β）。结果高血压组与正常组比较，各测值差异显著（Ｄｄ，２０．７３±２．８０ｍｍＶＳ１８．２０±３．０３ｍｍ，Ｐ＜０．００１；Ｄｓ，２２．１７±２．９０ｍｍＶＳ１９．８１±２．９３ｍｍ，Ｐ＜０．００１；ＩＭＴ，１．３９±０．４６ｍｍＶＳ１．１７±０．５０ｍｍ，Ｐ＜０．０５；Ｅｐ，１．４７±０．８４ＶＳ０．８１±０．６６，Ｐ＜０．００１；Ｅｓ，１１．９１±８．０４ＶＳ６．４９±３．９３，Ｐ＜０．００１；β，３．２４±０．４３ＶＳ２．９１±０．５２，Ｐ＜０．００１）。结论高血压可引起胸主动脉损害，导致ＩＭＴ增厚，内径扩大，弹性降低，僵硬度增大，可能与高血压患者的大动脉并发症有关。
Objective: To evaluate the effects of hypertension on the anatony and function of thoracic aorta. Methods:The diastolic and systolic diameter (Ddand Es)of thoracic aorta,its intimo-medal thickness(IMT), its peterson's and Young's elastic modules(Ep and Es),and its stiffness index (β)were measured in 41 normal subjects and 42 subjects with hypertension by transesophageal echocardiography.Results,Compared with the normal group,each measurement data was significantly different: Dd(20.73±2.80mm vs 18.20±3.03mm, P<0.001), Ds(22.17±2.9mm vs 19.81±2.93mm, P<0.001),IMT(1.39±0.66mm vs 1.17±0.50, P<0.05), Ep (1.47±0.84 vs 0.81±0.66, P<0.001),Es (11.91±8.04 vs 6.49±3.93, P<0.001),and β(3.24±0.43 vs 2.91±0.52, P<0.001). Conclusion: Hypertension can damage the thoracic aorta, resulting in the thickness of IMT, increase of diameter, decrease of elasticity,augmention of stiffness. These damages may be associated with the aortic complication of hypertension.
出处
《泰山医学院学报》
CAS
1998年第2期132-134,共3页
Journal of Taishan Medical College
关键词
高血压
胸主动脉
经食管超声
hypertension
thoracic aorta
tranesophageal echocardiography
