摘要
报告1例硬化性黏液水肿患者使用沙利度胺治疗后疗效显著。患者男,47岁。全身出现丘疹2年余,皮肤变硬半年。经治疗症状改善不明显,皮肤增厚、变硬,范围逐渐扩大,全身皮肤呈黑褐色。固定电泳检测发现单克隆IgG-λ。经皮损组织病理检查诊断为硬化性黏液水肿。给予沙利度胺50 mg,每日3次口服。3个月后随访,患者皮肤明显变薄、变软,肤色变浅。
This article reports a case of scleromyxedema with significant effect by thalidomide treatment. A 47-year-old male patient presented general firm papules for 2 years and hardening lesion for 6 months. After using acitretin 10 mg/d for 6 months, the skin was getting thicker and harder than before, and the lesion range expanded, hmnunofixation electrophoresis found monoclone IgG-λ. He was diagnosed as scleromyxedema by pathological examination. After given oral thalidminde 50 mg tid for 3 months, the skin became progressively softer, thinner and lighter.
出处
《临床皮肤科杂志》
CAS
CSCD
北大核心
2009年第12期796-798,共3页
Journal of Clinical Dermatology
