摘要
存在于血浆制品中的人细小病毒B19(human parvovirusB19,B19)是传播B19的潜在危险,尤其是B19可经污染的血浆制品的输注而在易感人群中传播。据认为,B19对普通的理化灭活方法有较强的抵抗力。然而,各项研究显示,B19对加热和低pH处理较敏感。因此,可以选择合适的方法来灭活B19。
The presence of human parvovirus B19 (B19) in plasma-derived products indicates a potential risk of B19 transmission, and especially, B19 may be transmitted by transfusion of the contaminated plasma and plasma-derived products in susceptible individuals. It is believed that B19 is more resistant to common physieochemical inactivation methods. However, the various studies show that B19 is more sensitive to heat and low pH treatment. So suitable methods may be selected to inactivate B19.
出处
《国际生物制品学杂志》
CAS
2009年第6期320-323,共4页
International Journal of Biologicals
关键词
细小病毒B19
人
生物制品
病毒灭活
Parvovirus B19, human
Biological products
Virus inactivation