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细菌性阴道病联合测定试剂盒方法学评价 被引量:9

Evaluation of the simultaneous determination kits for bacterial vaginosis
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摘要 目的分析细菌性阴道病联合测定试剂盒对细菌性阴道病(bacterial vaginosis,BV)的诊断效能,评估其临床应用价值。方法以Amsel法为诊断BV的参考方法,随机选取罗湖区妇幼保健院妇产科门诊患者98例,每位患者均一次性留取2份阴道分泌物标本,分别采用Amsel法和联合测定试剂盒进行检测;分析联合测定试剂盒检测结果阳性率、敏感性和特异性。结果Amsel法阳性率为21.4%,联合测定试剂盒阳性率为23.5%,二者差异无统计学意义(P>0.05)。联合测定试剂盒的敏感性为95.2%,特异性为96.1%,阳性预测值为87.8%,阴性预测值为98.7%,总有效率为95.9%。结论联合测定试剂盒检测BV有较高的敏感性、特异性和总有效率,可作为临床筛查BV的常规方法。 Objective To analyze the diagnostic efficacy of the simultaneous determination kits for bacterial vaginosis and to evaluate the value of clinical application. Methods Vaginal discharge of 98 patients from the department of Gynaecology and Obstetrics were tested by Amsel Standard and the simultaneous determination kits respectively. Amsel Standard was used as gold standard. The positive rates,sensitivity,specificity of the simultaneous de termination kits were analyzed. Results There was no statistical significance of the positive rate between Amsel Standard and the simultaneous determination kits (21.4 % vs 23.5 % ). The sensitivity, specificity, positive prediction value,negative prediction value,and the total effective rate of the simultaneous determination kits were 95.2%, 96. 1 % ,87.8 % ,98.7 % and 95.9 % in sequence. Conclusion The sensitivity, specificity and total effective rate of the simultaneous determination kits were all high; the kits could be used as routine method of screening bacterial vaginosis.
出处 《检验医学与临床》 CAS 2009年第23期1997-1998,共2页 Laboratory Medicine and Clinic
关键词 细菌性阴道病 诊断 检验 vaginosis,bacterial diagnosis detect
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