摘要
目的 观察结肠透析治疗慢性肾功能衰竭的疗效。方法将120例慢性肾功能衰竭患者随机分为2组，每组各60例，A组为结肠透析组，在常规治疗的基础上应用结肠透析机治疗；B组为常规治疗组．给予慢性肾功能衰竭的常规治疗。观察期为4周，观察血肌酐、尿素氮和24h尿蛋白定量，以血肌酐的变化判断透析的疗效。结果A、B组均可明显降低慢性肾功能衰竭患者的血肌酐水平，血肌酐分别由（363．97±82．34）μmol／L降为（280．87±87．52）μmol／L和（371．73±87．46）μmol／L降为（339．90±68．59）μmol／L，A组的治疗效果明显优于B组（P〈0．05）；对A组不同期的患者进行疗效对比，发现肾功能代偿期和失代偿期的疗效明显好于肾功能衰竭期，而前两者之间的疗效差别不明显。结论结肠透析治疗慢性肾功能衰竭疗效确切，尤其对血肌酐〈443μmol／L的患者能达到更好的治疗效果。
Objective To investigate the effects of colon dialysis on chronic renal failure（CRF）. Methods 120 patients with CRF were randomly divided into two groups and they were given the same conventional therapy including alimentary control, blood pressure control, etc. The A group （colon dialysis group, n = 60） was given colon dialysis , the B group （conventional therapy group, n = 60） was given conventional therapy for 4 weeks. The serum creatinine（SCr） , urea nitrogen, 24 h proteinuria were observed in two groups. The therapeutic effects of colon dialysis were assessed by the changes of SCr. Results The colon dialysis and conventional therapy can decrease the SCr from （363.97 ± 82.34 ）μmol/L to （280.87±87.52 ）μmol/L and （ 371.73 ± 87.46 ）μmol/L to （ 339.90± 68.59 ）μmol/L respectively. The former was more effective than the latter. The effects of colon dialysis in the renal function compensation stage and decompensation stage were more effective than in renal failure stage but no difference was detected between the former stages. Conclusions The colon dialysis has certain effects to CRF, especially to those with serum creatinine 〈 443 μmol/L can get more benefit.
出处
《中国综合临床》
2009年第12期1241-1243,共3页
Clinical Medicine of China
基金
河北省科学技术研究与发展计划项目（0720611037D）
关键词
结肠透析
慢性肾功能衰竭
血肌酐
Colon dialysis
Chronic renal failure
Serum creatinine
