摘要
目的观察早期血浆置换联合连续静脉-静脉血液滤过(CVVH)对高血脂性重症急性胰腺炎(HL-SAP)的治疗作用。方法将31例高血脂性重症急性胰腺炎患者分为2组:治疗组(早期血浆置换联合CVVH组,n=9)和对照组(n=22)。观察两组患者的血清三酰甘油(TG)的变化;比较两组症状缓解时间、住院时间和总的住院费用及并发症。结果①在入院时两组在TG、APACHEII评分差异无显著性,在入院第4天后两组TG均有明显下降(P<0.05),但治疗组与对照组比较下降更明显(P<0.05)。②治疗组在症状缓解时间和住院时间上较对照组均明显缩短,并发症和手术率降低,而总的住院费用增加不明显(P>0.05)。结论早期血浆置换联合CVVH能迅速降低血清TG,改善HL-SAP患者的全身状况并能有效减少并发症的发生,缩短症状缓解时间和住院时间而不明显增加住院费用。
[ Objective ] To evaluate the effect of earlier plasmapheresis combined with continuous Veno-Venous Hemofiltration （CVVH） in the treatment of patients with hyperlipidemic severe acute pancreatitis （HL-SAP）. [ Methods ] 31 patients with HL-SAP were divided into 2 groups： the treatment group were carried out with plasmapheresis combined with CVVH. Serum triglyceride, the remission times of signs and symptoms, total hospitalization duration and hospitalization expenses were compared respectively. [Results] In the 4th day, serum triglyceride levels reduced in both group, but decreased more distinctly in the treatment group （P 〈0.05）. Both of the remission times and hospitalization duration in the control group were significantly increased than those of the treatment group （P 〈0.05）, total hospitalization expenses in the treatment group increased lightly than those of the control group but had no statistic difference （P 〉0.05）. [ Conclusion ] Earlier plasmapheresis combined with CVVH can improve physical conditions and prevent the complications of patients with HL-SAP, decreased the remission times and hospitalization duration but didn＇t increase hospitalization expenses distinctly.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2009年第21期3323-3325,共3页
China Journal of Modern Medicine
关键词
胰腺炎
三酰甘油
血浆置换
血液滤过
pancreatitis
triglyceride
hemofiltration
plasmapheresis
