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全身性感染与Toll样受体2、4相关性研究进展 被引量：3

The New Progress of Study on Toll Like Receptor 2,4 in Correlation with Sepsis
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摘要 全身性感染是由感染所致的临床综合征,Toll样受体(TLR)导致的体内信号传导,使炎症反应级联放大,以及诱发机体免疫功能紊乱,致使机体对病原体清除效率降低。因此,阻断TLR传导通路可能会抑制全身性感染发生和发展的进程。 Sepsis is a clinical syndrome, which is induced by infection. The signal transduction of TLR makes inflammatory reaction cascade amplification. In addition, TLR may make resistance mechanism disordering, diminish the efficiency of pathogen clearance. Therefore, it could be an effective method that block the signal transduction of TLR to hamper the process of sepsis.
作者 张杰 万献尧
机构地区 大连医科大学附属一院重症医学科
出处 《医学与哲学（B）》 2009年第11期50-53,共4页 Medicine & Philosophy(B)
关键词 全身性感染 Toll样受体2 Toll样受体4 免疫耐受 sepsis，TLR2，TLR4，immunologic tolerance
分类号 R593.28 [医药卫生—内科学]
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二级参考文献15

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共引文献7

同被引文献40

引证文献3

二级引证文献9

医学与哲学（B）
2009年 第11期

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