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硝苯地平缓释片联合松弛疗法治疗中年人高血压的临床研究 被引量:1

A Clinical Study of the Combination Treatment of Sustained-release Nifedipine and Relaxation Therapy in Middle-aged Patients with Hypertension
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摘要 目的探讨硝苯地平缓释片联合松弛治疗对中年人高血压的影响。方法将90例中年高血压随机分为3组,每组各30例。Ⅰ组采用松弛疗法;Ⅱ组为硝苯地平缓释片治疗;Ⅲ组采用硝苯地平缓释片联合松弛治疗。疗程均为6个月。治疗前后进行3组症状自评量表评定、并记录血压值。结果3组治疗前症状自评量表与国内常模比较,除精神病因子外各因子评分差异均有极显著性(P<0.01),治疗后与国内常模比较,Ⅱ组差异仍有极显著性(P<0.01),Ⅰ、Ⅲ组差异均无显著性意义(P>0.05)。3组治疗后血压降至正常,与治疗前比较明显降低;且Ⅲ组治疗有效率明显高于其他2组(P<0.05 orP<0.01)。结论硝苯地平缓释片联合松弛治疗能改善患者的紧张、焦虑情绪,使患者血压降低。 Objective To evaluate the effect of sustained-release (SR) nifedipine combined with relaxation therapy on middle-aged patients with hypertension. Methods Ninety middle-aged patients with hypertension were randomly divided into 3 groups. For six months,Group Ⅰ was with relaxation therapy,Group Ⅱ was administered with nifedipine SR,and Group Ⅲ was with both nifedipine SR and relaxation therapy. All patients were assessed with psychotropic symptom checklist (SCL-90) and their blood pressures were monitored. Results Before the treatment,the SCL-90 factors,except for the mentalness factor of the three groups were significantly different from the normal (P〈0.01). After treatment, SCL-90 factors of all patients became normal except those of patients in Group Ⅱ(P〉0.05). The blood pressure of all groups decreased to normal level. In particular,the decrease was more significant for Group Ⅲ than the rest(P〈0.05 or P〈 0.01). Conclusion Sustained-release nifedipine combined with relaxation therapy could improve symptoms of middle-aged patients with hypertension by releasing anxiety and decreasing blood pressure.
出处 《实用临床医学(江西)》 CAS 2009年第9期13-16,共4页 Practical Clinical Medicine
关键词 硝苯地平缓释片 松弛治疗 高血压 中年人 sustained-release nifedipine relaxation therapy hypertension middle-aged patients
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  • 1姚树乔,孙学礼.医学心理学[M].5版.北京:人民卫生出版社.2008:50.221-222.
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