摘要
为探讨焦炉逸散物及高温对作业工人血浆HSP70抗体滴度及肿瘤坏死因子（TNF）的影响，运用酶联免疫吸附鉴定法检测了85名焦炉工和73名非焦炉工血浆HSP70抗体滴度和TNF－α的含量。结果显示，焦炉工有51人出现1：10抗体阳性，21人出现1：20抗体阳性，分别占60％、28．2％；非焦炉工有23人出现1：10抗体阳性，11人出现1：20抗体阳性，分别占31．5％、15．1％，两组相比，差异有显著性（P＜0．05）。TNF的含量焦炉组明显高于对照组，差异有显著性（P＜0．05）。结果表明，焦炉逸散物和高温可导致机体受损、免疫功能发生紊乱。
In order to explore the effects of coke oven emission (COE) and high temperature on the dilution of antibody against HSP70 and tumor necrosis factor (TNF ) in plasma of workers,the dilution of antibody and contents of TNF-αof 85 exposed workers and 73 control workers were determined with enzyme-linked immunosorbent assay. The results showed that 51 exposed workers had a dilution of 1: 10 and 24 ones of 1: 20 whose positive rates were 60%, 28. 2% respectively, while in the control group there were 23 with 1: 10 and 11 with 1: 20 whose positive rates were 31. 5%,1 5. 1 % respectively. There existed a significant increase of TNF-α and the dilution of antibody against HSP70 (P<0. 05) in exposed group. These results suggested that COE and high temperature could result a immune disorders and cell damage in exposed workers.
出处
《工业卫生与职业病》
CAS
CSCD
1998年第6期343-345,共3页
Industrial Health and Occupational Diseases
基金
湖北省科委资助
武汉钢铁公司资助
关键词
焦炉逸散物
热应激蛋白
抗体滴度
肿瘤坏死因子
Coke oven emission (COE)
High temperature
Heat stress protein
Dilution of antibody
Tumor necrosis factor (TNF)
Enzyme linked immunosorbent assay
