摘要
目的探讨血小板降低对重症急性胰腺炎（SAP）的坏死程度及预后的影响。方法将四川大学华西医院2005年1月至2006年12月收治的SAP233例，按血小板是否为正常值，分成血小板降低组（〈100×10^9／L）和血小板正常组（≥100×10^9／L），分析两组血小板变化与胰腺坏死程度及预后的关系。结果血小板计数降低组99例，占42．49％；血小板计数正常组134例，占57．51％。两组在APACHEⅡ评分、预后、有无胰腺坏死及胰腺坏死程度有统计学意义（P〈0．05），两组RANSON评分无统计学意义。结论血小板降低对提示胰腺病情程度、是否存在胰腺坏死、推测疾病预后有一定临床指导意义。
Objective To study the significance of the change of platelet count for the degree of necrosis and prognosis of severe acute pancreatitis. Methods The 223 cases of SAP treated in our hospital from January 2005 to December 2006 were divided into group of decreases of platelet count （〈100×10^9/L） （group A） and group of normal of platelet count （≥100×10^9/L） （group B）. The scores of APACHEII and Ranson, degrees of pancreatic necrosis and mortality and the degree of pancreatic necrosis were analyzed in and compared between the 2 groups. Results There were 99 cases in group A （42.49 % ）. The scores of APACHEII and the degree of pancreatic necrosis and mortality and the degree of pancreatic necrosis were significantly more severe in group than in group B （P〈0.05）. There was no marked difference in the scores of Ranson between the two groups（P〉0.05）. Conclusion Platelet count decrease is of certain clinical significance for judging severity of pancreatitis, panreatic necrosis and predicting its prognosis.
出处
《中华肝胆外科杂志》
CAS
CSCD
北大核心
2009年第11期826-827,共2页
Chinese Journal of Hepatobiliary Surgery
