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脱氢枞胺衍生物的合成与抗菌活性 被引量:4

Synthesis and bactericidal activity of derivatives of dehydroabietylamine
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摘要 Three derivatives of dehydroabietylamine were synthesized from dehydroabietylamine through trifluoro-acetyltion,nitration and hydrolysis.Two of them were first reported as new compounds.The compounds were characterized by FT-IR,1H NMR,EI-MS,elemental analyses and HRMS.Their bactericidal activities were investigated,and the results indicated that 12-nitro-dehydroabietylamine and 12,14-dinitro-dehydroabietylamine had strong bactericidal activity against E.coli,Staphylococcus aureus,Pseudomonas fluorescens. Three derivatives of dehydroabietylamine were synthesized from dehydroabietylamine through trifluoro-acetyltion,nitration and hydrolysis.Two of them were first reported as new compounds.The compounds were characterized by FT-IR,1H NMR,EI-MS,elemental analyses and HRMS.Their bactericidal activities were investigated,and the results indicated that 12-nitro-dehydroabietylamine and 12,14-dinitro-dehydroabietylamine had strong bactericidal activity against E.coli,Staphylococcus aureus,Pseudomonas fluorescens.
出处 《化工学报》 EI CAS CSCD 北大核心 2009年第12期3077-3081,共5页 CIESC Journal
基金 国家自然科学基金项目(30771688)~~
关键词 脱氢枞胺 合成 表征 抗菌 dehydroabietylamine synthesis characterization bactericidal activity
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