摘要
102例受试者，包括不明原因晕厥患者72例，无晕厥史的正常人30例，随机分为异丙肾上腺素（ISO）组和硝酸甘油（NG）组，观察倾斜试验中是否可诱发与临床症状相一致的晕厥或晕厥先兆以及相伴随的心率、血压变化。ISO组病人42例，正常人14例，副作用多，常见为心悸（20例，占35．7％），其中4例出现频发室性早搏，不能耐受而终止检查。NG组病人30例，正常人16例，无心悸、心律失常等副作用，仅1例（2．2％）发生头痛，尚可耐受。ISO组敏感性和特异性分别为76.3％、76．9％；NG组为713％、87．5％，两组之间无显著性差异（P＞0．05）。对NG组中的30例随机进行了重复试验，两次均阳性13例，均阴性15例，两次试验的符合率为93.3％（28／30）。表明倾斜试验中舌下含服NG对诊断血管迷走性是厥安全、可靠，有一定临床价值。
Head-up tilt test with infusion of isoproterenol or sublingual nitroglycerin was randomly performed in 72 patients with syncope of unknown origin and 30 volunteer normal control subjects. Forty-two patients and 14 control subjects underwent tilt test with infusion of isoproterenol, Thirty patients and 16 control subjects underwent tilt test with sublingual nitroglycerin. More side effects were observed in patients who underwent tilt test with infusion of isoproterenol (35.7%) compared to those with sublingual nitroglycerin (2. 2%). The sensibility and specificity with infusion of isoproterenol were 76.3% and 76.9%,with sublingual nitroglycerin were 73. 3%,87.5%. The difference between these 2 groups was not significant (P >0.05). 30 of the NG group received test again, 13 cases were both positive, 15 cases were both negative. The corresponding rate between 2 tests was 93.3% (28/30). The resutls suggested that head-up tilt test combined with sublingual nitroglycerin was a safe and valuable tool in the diagnosis of neurocardiac syncope.
出处
《临床心血管病杂志》
CAS
CSCD
北大核心
1998年第6期341-343,共3页
Journal of Clinical Cardiology
