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多发性骨髓瘤常用实验诊断方法评价 被引量:5

Evaluation of labouratory tests for diagnosis of multiple myeloma
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摘要 目的:比较血清蛋白电泳(琼脂糖凝胶法)、尿本周氏蛋白、骨髓细胞学等实验室指标对多发性骨髓瘤的诊断价值,找出经济、简便、快速的敏感指标。方法:分析多发性骨髓瘤的诊断过程,计算血清蛋白电泳、尿本周氏蛋白、骨髓细胞学诊断的敏感度和特异度。结果:琼脂糖凝胶血清蛋白电泳的敏感度是96.6%,特异度96.4%;尿本周氏蛋白的敏感度是10.5%,特异度98.2%;骨髓细胞学的敏感度是51.7%,特异度100%。.结论:琼脂糖凝胶血清蛋白电泳的敏感度最高,且简便、快速、经济实用。 Objective:To evaluate the valus of serum protein electrophoresis (agarose gel), Bence -jones protein, bonemarrow cytology tests in multiple myeloma(MM) diagnosis. Methods:To analyze the diagnosis of MM,calculate the sensitivity and sptcificity of serum protein electrophoresis, Bence -jones protein and bone marrow cytology of. Results:The sensitivity of the serum protein gel electrophoresis was 96.6% ,and the specificity was 96.4% ;Bence -jones protein sensitivity was 10.5 %, specificity was 98.2% ;bone marrow cytology sensitivity was 51.7 % and specificity 100%. Conclusion: The serum protein gel electrophoresis test is with the highest sensitivity, and simple, quick, economical and practical for the diagnosis of MM.
出处 《现代肿瘤医学》 CAS 2009年第11期2217-2219,共3页 Journal of Modern Oncology
关键词 多发性骨髓瘤 血清蛋白电泳 敏感度 特异度 mutiple myeloma protein electrophoresis sensitivity specificity
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  • 1Kyle RA,Rajkumar SV.Monoclonal gammopathies of undetermined Significance:a review[J].Immunological Reviews,2003,194:112-139.
  • 2Kyle RA,Therneau TM,Rajkumar SV,et al.A long-term study of prognosis in monoclonal gammopathy of undetermined significance[J].N Engl J Med,2002,346:564-569.
  • 3陈楠.单克隆免疫球蛋白病肾脏损害[J].中国实用内科杂志,2002,22(9):522-525. 被引量:3

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